THAP1 Protein (His tag)
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- Target See all THAP1 Proteins
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This THAP1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product THAP1 Protein
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- Comment
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Synonyms: THAP domain-containing protein 1, DYT6
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol, 1 MM DTT, 0.2 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- THAP1 (THAP Domain Containing, Apoptosis Associated Protein 1 (THAP1))
- Alternative Name
- THAP1 (THAP1 Products)
- Synonyms
- THAP1 Protein, thap1-a Protein, DYT6 Protein, 4833431A01Rik Protein, AW490810 Protein, zgc:136597 Protein, THAP domain containing, apoptosis associated protein 1 Protein, THAP domain containing 1 Protein, THAP domain containing, apoptosis associated protein 1 L homeolog Protein, thap1 Protein, THAP1 Protein, thap1.L Protein, Thap1 Protein
- Background
- THAP domain-containing protein 1, also known as THAP1, is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAPtype zinc finger, a conserved DNA-binding domain. It is a DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. THAP1 may also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. Recombinant human THAP1protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 27.5 kDa (237aa)
- NCBI Accession
- NP_060575
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