HMGCR Protein (AA 588-887) (His tag)

Catalog No. ABIN7121606

Product Details

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Protein Type: Recombinant

Protein Characteristics: AA 588-887

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HMGCR protein is labelled with His tag.

Application: Western Blotting (WB), ELISA

Purity: Greater than 95 % as determined by SDS-PAGE

Sterility: 0.2 μm filtered

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/mL in sterile distilled water by gentle pipetting 2-3 times, don't vortex

Buffer: Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5 % trehalose, pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: -20°C for 12 months as lyophilized, 2-8°C for 1 month under sterile conditions after reconstitution

Expiry Date: 12 months

Target Details

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: HMGCR (HMGCR Products)

Synonyms: HMGR Protein, LDLCQ3 Protein, hmg-coa-r Protein, HMG-CoAR Protein, Red Protein, 3H3M Protein, BcDNA:LD15354 Protein, CG10367 Protein, Clb Protein, DmHMG-CoAr Protein, Dmel\\CG10367 Protein, HMGCR Protein, HMGCR_Dm Protein, HMGCoAR Protein, HMGCoARr Protein, HMGCoAr Protein, HmG-CoAR Protein, Hmg Protein, bro1 Protein, bs32f05.y1 Protein, clb Protein, hmgc Protein, hmgcr Protein, hmgrc Protein, l(3)01152 Protein, l(3)04684 Protein, hmgcr2 Protein, im:6912716 Protein, zgc:110746 Protein, 3-hydroxy-3-methylglutaryl-CoA reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase Protein, HMG Coenzyme A reductase Protein, 3-hydroxy-3-methylglutaryl-CoA reductase b Protein, HMGCR Protein, hmgcr.L Protein, Hmgcr Protein, hmgcrb Protein

Background: 3 hydroxy 3 methylglutaryl CoA reductase, 3 hydroxy 3 methylglutaryl Coenzyme A reductase, 3 hydroxymethylglutaryl CoA reductase, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH), 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3H3M, HMDH_HUMAN, HMG CoA reductase

Molecular Weight: 32.9 kDa

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha