IL1RL1 Protein (AA 1-328, Isoform 2) (Fc Tag)
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- Target See all IL1RL1 Proteins
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Isoform 2, AA 1-328
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL1RL1 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to human IL-33.
- Cross-Reactivity
- Human
- Characteristics
- Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL1RL1 Protein
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Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) protein (His tag)
IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) (Active) protein (His tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 1 Receptor-Like 1 (IL1RL1) protein (His tag)IL1RL1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 350-556) protein (His tag)Crystallography grade IL1RL1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 356-567) protein (His tag)Crystallography grade IL1RL1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-328) protein (His tag)Crystallography grade IL1RL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 27-332) protein (His tag)Crystallography grade IL1RL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-556) protein (rho-1D4 tag)Crystallography grade IL1RL1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 27-567) protein (rho-1D4 tag)Crystallography grade IL1RL1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 1 Receptor-Like 1 (IL1RL1) (AA 19-323) (Active) protein (Fc Tag)IL1RL1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Interacts with human IL-33.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.2.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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- Target
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
- Alternative Name
- ST2 (IL1RL1 Products)
- Synonyms
- DER4 Protein, Fit-1 Protein, Ly84 Protein, ST2L Protein, St2 Protein, St2-rs1 Protein, T1 Protein, T1/ST2 Protein, FIT-1 Protein, IL33R Protein, ST2 Protein, ST2V Protein, FIT1 Protein, interleukin 1 receptor-like 1 Protein, interleukin 1 receptor like 1 Protein, Il1rl1 Protein, IL1RL1 Protein
- Background
- The ST2 (Interleukin-1 receptor-like 1, Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
- Molecular Weight
- ~90kDa (SDS-PAGE)
- UniProt
- Q01638
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