FTO Protein (AA 2-505) (His tag)
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- Target See all FTO Proteins
- FTO (Fat Mass and Obesity-Associated (FTO))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-505
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FTO protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human FTO (aa 2-505) is fused at the N-terminus to a His-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FTO Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 150 mM NaCl.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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- Target
- FTO (Fat Mass and Obesity-Associated (FTO))
- Alternative Name
- FTO (FTO Products)
- Synonyms
- AW743446 Protein, mKIAA1752 Protein, RGD1305121 Protein, FTO, alpha-ketoglutarate dependent dioxygenase Protein, fat mass and obesity associated Protein, fat mass and obesity associated L homeolog Protein, FTO Protein, Fto Protein, fto.L Protein
- Background
- FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
- Molecular Weight
- ~65kDa (SDS-PAGE)
- UniProt
- Q9C0B1
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