Lamin A/C Protein (LMNA) (AA 1-662) (His tag)

Catalog No. ABIN1474607

Product Details

Target: Lamin A/C (LMNA)

Protein Type: Recombinant

Protein Characteristics: AA 1-662

Origin: Rat

Source: Yeast

Purification tag / Conjugate: This Lamin A/C protein is labelled with His tag.

Application: ELISA

Sequence: METPSQRRPT RSGAQASSTP LSPTRITRLQ EKEDLQELND RLAVYIDRVR SLETENAGLR LRITESEEVV SREVSGIKAA YEAELGDARK TLDSVAKERA RLQLELSKVR EEFKELKARN TKKEGDLLAA QARLKDLEAL LNSKEAALST ALSEKRTLEG ELHDLRGQVA KLEAALGEAK KQLQDEMLRR VDAENRLQTL KEELDFQKNI YSEELRETKR RHETRLVEID NGKQREFESR LADALQELRA QHEDQVEQYK KELEKTYSAK LDNARQSAER NSNLVGAAHE ELQQSRIRID SLSAQLSQLQ KQLAAKEAKL RDLEDSLARE RDTSRRLLAE KEREMAEMRA RMQQQLDEYQ ELLDIKLALD MEIHAYRKLL EGEEERLRLS PSPTSQRSRG RASSHSSQSQ GGGSVTKKRK LESSESRSSF SQHARTSGRV AVEEVDEEGK FVRLRNKSNE DQSMGNWQIK RQNGDDPLMT YRFPPKFTLK AGQVVTIWAS GAGATHSPPT DLVWKAQNTW GCGTSLRTAL INATGEEVAM RKLVRSLTMV EDNDDEEEDG DELLHHHRGS HCSSSGDPAE YNLRSRTVLC GTCGQPADKA ASGSGAQVGG SISSGSSASS VTVTRSFRSV GGSGGGSFGD NLVTRSYLLG NSSPRTQSSQ NC

Specificity: Rattus norvegicus (Rat)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: Lamin A/C (LMNA)

Alternative Name: Prelamin-A/C (Lmna) (LMNA Products)

Synonyms: CDCD1 Protein, CDDC Protein, CMD1A Protein, CMT2B1 Protein, EMD2 Protein, FPL Protein, FPLD Protein, FPLD2 Protein, HGPS Protein, IDC Protein, LDP1 Protein, LFP Protein, LGMD1B Protein, LMN1 Protein, LMNC Protein, LMNL1 Protein, PRO1 Protein, Dhe Protein, 2459 Protein, 74/76 Protein, CG6944 Protein, D5 Protein, DM[[O]] Protein, Dm Protein, Dm(0) Protein, Dm0 Protein, Dm1 Protein, Dm2 Protein, DmLamin Protein, DmO Protein, Dm[[0]] Protein, Dm[[1]] Protein, Dm[[2]] Protein, Dm[[mit]] Protein, Dm[[o]] Protein, Dmel\\CG6944 Protein, Dmo Protein, LAM Protein, Lam Dm[[0]] Protein, Lam(Dm0) Protein, LamDm[[0]] Protein, LamDm[[o]] Protein, Lam[[Dm0]] Protein, Lamin Dm[[0]] Protein, jf27 Protein, l(2)04643 Protein, l(2)25Ec Protein, l(2)gdh-7 Protein, l(2)gdh7 Protein, l(2)jf27 Protein, lam Protein, lamDm0 Protein, lamDm[[0]] Protein, lamin Protein, lamin Dm0 Protein, lamin Dm[[0]] Protein, misg Protein, nlam Protein, cb948 Protein, fk66d12 Protein, wu:fk66d12 Protein, lmna-A Protein, fpl Protein, idc Protein, lfp Protein, cddc Protein, emd2 Protein, fpld Protein, hgps Protein, ldp1 Protein, lmn1 Protein, lmnc Protein, pro1 Protein, cdcd1 Protein, cmd1a Protein, cmt2b1 Protein, lgmd1b Protein, Lamin-A Protein, lamin-L(III)-like Protein, lamin A/C Protein, lamin A Protein, Lamin Protein, lamin A/C L homeolog Protein, lamin-L(III)-like Protein, LMNA Protein, Lmna Protein, Lam Protein, lmna Protein, lmna.L Protein, LMINA Protein

Background: Recommended name: Prelamin-A/C Cleaved into the following chain: 1.
Lamin-A/C

UniProt: P48679

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus