Elastase 4 Protein (AA 17-268) (His tag)
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- Target See all Elastase 4 (CTRC) products
- Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 17-268
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Elastase 4 protein is labelled with His tag.
- Purpose
- Recombinant Human Chymotrypsin-C/CTRC (C-6His)
- Sequence
- CGVPSFPPNL SARVVGGEDA RPHSWPWQIS LQYLKNDTWR HTCGGTLIAS NFVLTAAHCI SNTRTYRVAV GKNNLEVEDE EGSLFVGVDT IHVHKRWNAL LLRNDIALIK LAEHVELSDT IQVACLPEKD SLLPKDYPCY VTGWGRLWTN GPIADKLQQG LQPVVDHATC SRIDWWGFRV KKTMVCAGGD GVISACNGDS GGPLNCQLEN GSWEVFGIVS FGSRRGCNTR KKPVVYTRVS AYIDWINEKM QLVDHHHHHH
- Characteristics
- Recombinant Human Chymotrypsin-C/CTRC produced by transfected human cells is a secreted protein with sequence (Cys17-Leu268) of Human CTRC fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Chymotrypsin C (Caldecrin) (CTRC) (AA 1-268) protein (GST tag)
CTRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chymotrypsin C (Caldecrin) (CTRC) (AA 170-268) protein (GST tag)CTRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chymotrypsin C (Caldecrin) (CTRC) (AA 30-268) protein (His tag)Crystallography grade CTRC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Chymotrypsin C (Caldecrin) (CTRC) (AA 30-268) protein (His tag)Crystallography grade CTRC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
- Alternative Name
- chymotrypsin-c (CTRC Products)
- Synonyms
- CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein
- Sub Type
- Fusionprotein
- Background
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Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers to cleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
Alternative Names: Chymotrypsin-C, Caldecrin, CTRC, CLCR - Molecular Weight
- 29 kDa
- UniProt
- Q99895
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