Elastase 4 Protein (His tag)
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- Target See all Elastase 4 (CTRC) products
- Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Elastase 4 protein is labelled with His tag.
- Purpose
- Recombinant Human Chymotrypsin C Protein (His Tag)
- Sequence
- Cys17-Leu268
- Characteristics
- Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Chymotrypsin C (Caldecrin) (CTRC) (AA 1-268) protein (GST tag)
CTRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chymotrypsin C (Caldecrin) (CTRC) (AA 170-268) protein (GST tag)CTRC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chymotrypsin C (Caldecrin) (CTRC) proteinCTRC Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
- Alternative Name
- Chymotrypsin C (CTRC Products)
- Synonyms
- CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein
- Background
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Background: Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
Synonym: Chymotrypsin-C, Caldecrin, CTRC, CLCR
- Molecular Weight
- 29.0 kDa
- UniProt
- Q99895
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