Cadherin 8 Protein (CDH8) (AA 30-621) (His tag)
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- Target See all Cadherin 8 (CDH8) Proteins
- Cadherin 8 (CDH8)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-621
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Cadherin 8 protein is labelled with His tag.
- Purpose
- Recombinant Human Cadherin-8/CDH8 (C-6His)
- Sequence
- APMNQSQVLM SGSPLELNSL GEEQRILNRS KRGWVWNQMF VLEEFSGPEP ILVGRLHTDL DPGSKKIKYI LSGDGAGTIF QINDVTGDIH AIKRLDREEK AEYTLTAQAV DWETSKPLEP PSEFIIKVQD INDNAPEFLN GPYHATVPEM SILGTSVTNV TATDADDPVY GNSAKLVYSI LEGQPYFSIE PETAIIKTAL PNMDREAKEE YLVVIQAKDM GGHSGGLSGT TTLTVTLTDV NDNPPKFAQS LYHFSVPEDV VLGTAIGRVK ANDQDIGENA QSSYDIIDGD GTALFEITSD AQAQDGIIRL RKPLDFETKK SYTLKVEAAN VHIDPRFSGR GPFKDTATVK IVVEDADEPP VFSSPTYLLE VHENAALNSV IGQVTARDPD ITSSPIRFSI DRHTDLERQF NINADDGKIT LATPLDRELS VWHNITIIAT EIRNHSQISR VPVAIKVLDV NDNAPEFASE YEAFLCENGK PGQVIQTVSA MDKDDPKNGH YFLYSLLPEM VNNPNFTIKK NEDNSLSILA KHNGFNRQKQ EVYLLPIIIS DSGNPPLSST STLTIRVCGC SNDGVVQSCN VEAYVLPIGL SMVDHHHHHH
- Characteristics
- Recombinant Human Cadherin-8/CDH8 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala30-Met621) of Human CDH8 fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CDH8 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- Cadherin 8 (CDH8)
- Alternative Name
- Cadherin-8 (CDH8 Products)
- Synonyms
- AI851472 Protein, cad8 Protein, cadherin-8 Protein, Nbla04261 Protein, cadherin 8 Protein, cadherin 8, type 2 Protein, Cdh8 Protein, CDH8 Protein
- Sub Type
- Fusionprotein
- Background
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Cadherin-8 (CDH8) is a type II classical cadherin from the cadherin superfamily. Member of the Cadherin superfamily are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. The extracellular domain of CDH8 contains five cadherin domains. CDH8 is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Alternative Names: Cadherin-8, CDH8 - Molecular Weight
- 66.07 kDa
- UniProt
- P55286
- Pathways
- Cell-Cell Junction Organization
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