Uroplakin 2 Protein (UPK2) (AA 26-155) (His tag)
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- Target See all Uroplakin 2 (UPK2) Proteins
- Uroplakin 2 (UPK2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-155
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This Uroplakin 2 protein is labelled with His tag.
- Purpose
- Recombinant Human Uroplakin-2/UPK2 (C-6His)
- Sequence
- DFNISSLSGL LSPALTESLL VALPPCHLTG GNATLMVRRA NDSKVVTSSF VVPPCRGRRE LVSVVDSGAG FTVTRLSAYQ VTNLVPGTKF YISYLVKKGT ATESSREIPM STLPRRNMES IGLGMARTGG VDHHHHHH
- Characteristics
- Recombinant Human Uroplakin-2/UPK2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp26-Gly155) of Human UPK2 fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product UPK2 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- Uroplakin 2 (UPK2)
- Alternative Name
- Uroplakin-2 (UPK2 Products)
- Synonyms
- UPK2 Protein, UP2 Protein, UPII Protein, AW491716 Protein, uroplakin 2 Protein, UPK2 Protein, upk2 Protein, Upk2 Protein
- Sub Type
- Fusionprotein
- Background
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Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
Alternative Names: Uroplakin-2, UP2, Uroplakin II, UPII, UPK2 - Molecular Weight
- 14.84 kDa
- UniProt
- O00526
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