FK506 Binding Protein 7 (FKBP7) (AA 24-222) protein (His tag)

Details for Product No. ABIN1691411, Supplier: Log in to see
Protein Name
  • FKBP
  • si:dz167c3.2
  • FKBP-7
  • DKFZp469I2124
  • FKBP23
  • PPIase
  • 23kDa
  • FK506 binding protein 7
  • FK506 binding protein 7 L homeolog
  • fkbp7
  • FKBP7
  • fkbp7.L
  • Fkbp7
Protein Characteristics
AA 24-222
2
1
1
1
1
1
1
1
1
1
1
Origin
Human
9
3
Source
Mammalian Cells
4
2
2
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
His tag
Application
Functional Studies (Func)
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Purpose Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP7/FKBP7 (C-6His)
Sequence QRQKKEESTE EVKIEVLHRP ENCSKTSKKG DLLNAHYDGY LAKDGSKFYC SRTQNEGHPK WFVLGVGQVI KGLDIAMTDM CPGEKRKVVI PPSFAYGKEG YAEGKIPPDA TLIFEIELYA VTKGPRSIET FKQIDMDNDR QLSKAEINLY LQREFEKDEK PRDKSYQDAV LEDIFKKNDH DGDGFISPKE YNVYQHDELV DHHHHHH
Characteristics Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP7/FKBP7 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln24-Leu222) of Human FKBP7 fused with a 6His tag at the C-terminus.
Purity > 95 % as determined by reducing SDS-PAGE.
Sterility 0.2 μm filtered
Endotoxin Level Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Sub Type Fusionprotein
Background Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.
Alternative Names: Peptidyl-Prolyl Cis-Trans Isomerase FKBP7, PPIase FKBP7, 23 kDa FK506-Binding Protein, 23 kDa FKBP, FKBP-23, FK506-Binding Protein 7, FKBP-7, Rotamase, FKBP7, FKBP23
Molecular Weight 23.94 kDa
UniProt Q9Y680
Restrictions For Research Use only
Format Liquid
Reconstitution It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,1 mM GaCl2,10 % Glycerol, pH 7.5.
Handling Advice Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Storage -80 °C
Storage Comment Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
Expiry Date 6 months
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