ERP44 Protein (AA 30-402) (His tag)
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- Target See all ERP44 Proteins
- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 30-402
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This ERP44 protein is labelled with His tag.
- Purpose
- Recombinant Human ER Resident Protein 44/ERp44/TXNDC4 (C-6His)
- Sequence
- EITSLDTENI DEILNNADVA LVNFYADWCR FSQMLHPIFE EASDVIKEEF PNENQVVFAR VDCDQHSDIA QRYRISKYPT LKLFRNGMMM KREYRGQRSV KALADYIRQQ KSDPIQEIRD LAEITTLDRS KRNIIGYFEQ KDSDNYRVFE RVANILHDDC AFLSAFGDVS KPERYSGDNI IYKPPGHSAP DMVYLGAMTN FDVTYNWIQD KCVPLVREIT FENGEELTEE GLPFLILFHM KEDTESLEIF QNEVARQLIS EKGTINFLHA DCDKFRHPLL HIQKTPADCP VIAIDSFRHM YVFGDFKDVL IPGKLKQFVF DLHSGKLHRE FHHGPDPTDT APGEQAQDVA SSPPESSFQK LAPSEYRYTL LRDVDHHHHH H
- Characteristics
- Recombinant Human Thioredoxin domain-containing protein 4/TXNDC4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu30-Asp402) of Human TXNDC4 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ERP44 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris HCl,10 % glycerol,PH7.5.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- ERP44 (Endoplasmic Reticulum Protein 44 (ERP44))
- Alternative Name
- TXNDC4 (ERP44 Products)
- Synonyms
- PDIA10 Protein, TXNDC4 Protein, 1110001E24Rik Protein, AI849526 Protein, AL033348 Protein, Txndc4 Protein, BWK4 Protein, txndc4 Protein, zgc:77883 Protein, endoplasmic reticulum protein 44 Protein, ERP44 Protein, Erp44 Protein, erp44 Protein
- Sub Type
- Fusionprotein
- Background
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Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.
Alternative Names: Thioredoxin domain-containing protein 4, ER protein 44, KIAA0573, TXNDC4 - Molecular Weight
- 44.2 kDa
- UniProt
- Q9BS26
- Pathways
- Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome
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