CALCB Protein (AA 1-127) (GST tag)
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- Target See all CALCB Proteins
- CALCB (Calcitonin-Related Polypeptide beta (CALCB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-127
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CALCB protein is labelled with GST tag.
- Purpose
- Recombinant Human Calcitonin Gene-Related Peptide 2/CALCB (N-GST)
- Sequence
- MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSENLY FQGHMGFRKF SPFLALSILV LYQAGSLQAA PFRSALESSP DPATLSKEDA RLLLAALVQD YVQMKASELK QEQETQGSSS AAQKRACNTA TCVTHRLAGL LSRSGGMVKS NFVPTNVGSK AFGRRRRDLQ A
- Characteristics
- Recombinant Human Calcitonin gene-related peptide 2/CALCB is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala127) of Human CALCB fused with a GST tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 50 % glycerol.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- CALCB (Calcitonin-Related Polypeptide beta (CALCB))
- Alternative Name
- CALCB (CALCB Products)
- Synonyms
- CRSP Protein, CRSP-1 Protein, CRSP1 Protein, CALCB Protein, CALC2 Protein, CGRP-II Protein, CGRP2 Protein, Calc2 Protein, calcitonin-related polypeptide beta Protein, calcitonin related polypeptide beta Protein, calcitonin gene-related peptide 2 Protein, calcitonin-related polypeptide, beta Protein, CALCB Protein, LOC698209 Protein, Calcb Protein
- Sub Type
- Fusionprotein
- Background
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CALCB is a member of the calcitonin family. CALCB is produced in both peripheral and central neurons. It is a potent peptide vasodilator and can function in the transmission of pain. In the spinal cord, the function and expression of CGRP may differ depending on the location of synthesis. CALCB is derived mainly from the cell bodies of motor neurons when synthesized in the ventral horn of the spinal cord and may contribute to the regeneration of nervous tissue after injury.
Alternative Names: Calcitonin gene-related peptide 2, CALC2, Beta-type CGRP, Calcitonin gene-related peptide II, CALCB. - Molecular Weight
- 40.9 kDa
- UniProt
- P10092
- Pathways
- Hormone Activity
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