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SELPLG Protein (AA 42-307) (Fc Tag)

SELPLG Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1945375
  • Target See all SELPLG Proteins
    SELPLG (Selectin P Ligand (SELPLG))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 42-307
    Origin
    • 6
    • 4
    • 2
    • 1
    Mouse
    Source
    • 7
    • 5
    • 1
    Human Cells
    Purification tag / Conjugate
    This SELPLG protein is labelled with Fc Tag.
    Purpose
    Recombinant Mouse P-Selectin Glycoprotein Ligand 1/PSGL-1/CD162 (C-Fc)
    Sequence
    QVVGDDDFED PDYTYNTDPP ELLKNVTNTV AAHPELPTTV VMLERDSTSA GTSERATEKI ATTDPTAPGT GGTAVGMLST DSATQWSLTS VETVQPASTE VETSQPAPME AETSQPAPME AETSQPAPME ADTSKPAPTE AETSKPAPTE AETSQPAPNE AETSKPAPTE AETSKPAPTE AETTQLPRIQ AVKTLFTTSA ATEVPSTEPT TMETASTESN ESTIFLGPSV THLPDSGLKK GLIVTPGNSP APTLPGSSDL IPVKQCVDDI EGRMDEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK
    Characteristics
    Recombinant Mouse SELPLG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 42-307) of Mouse SELPLG fused with a FC tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SELPLG Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SELPLG (Selectin P Ligand (SELPLG))
    Alternative Name
    SELPLG (SELPLG Products)
    Synonyms
    CD162 Protein, CLA Protein, PSGL-1 Protein, PSGL1 Protein, SELPLG Protein, SELPG Protein, Psgl-1 Protein, Psgl1 Protein, Selp1 Protein, Selpl Protein, selectin P ligand Protein, selectin, platelet (p-selectin) ligand Protein, clasper Protein, SELPLG Protein, Selplg Protein, cla Protein
    Background
    P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 can also bind to other two members of the selectin family, E-selectin (endothelial) and L-selectin (leukocyte), but binds best to P-selectin.
    Molecular Weight
    54.7 kDa
    UniProt
    Q62170
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