Betacellulin Protein (BTC) (AA 32-111)
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- Target See all Betacellulin (BTC) Proteins
- Betacellulin (BTC)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 32-111
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Characteristics
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ED50 <0.5 ng/mL, measured by a cell proliferation assay using3T3cells, corresponding to a specific activity of>2× 10^6 units/mg.
AA 32-111, expressed with an N-terminal Met. - Purity
- > 95 % by SDS-PAGE analysis.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product BTC Protein
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 1-178) protein (GST tag)BTC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 70-178) protein (GST tag)BTC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-111) protein (rho-1D4 tag)Crystallography grade BTC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Betacellulin (BTC) (AA 32-178) protein (rho-1D4 tag)Crystallography grade BTC Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Betacellulin (BTC) (AA 32-111) protein (rho-1D4 tag)Crystallography grade BTC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Betacellulin (BTC) (AA 32-177) protein (rho-1D4 tag)Crystallography grade BTC Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Betacellulin (BTC) (AA 32-118) protein (His tag)BTC Origin: Human Host: Yeast Recombinant > 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against 50 mM Tris, 300 mM NaCl, pH 9.0.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant mouse Betacellulin (rmBetacellulin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmBetacellulin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- Betacellulin (BTC)
- Alternative Name
- Betacellulin (BTC Products)
- Synonyms
- BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
- Background
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Betacellulin is a pleiotropic cytokine that belongs to the Epidermal Growth Factor (EGF) family. Like other members of the EGF family, Betacellulin possesses a conserved sequence of 35-40 amino acids which contain 3 disulfide bonds formed by 6 cysteines. Betacellulin is unique in the EGF family since it can bind and activate a broad spectrum of ErbB receptors. Functionally, Betacellulin plays a role in the development of the pancreas by activating signaling pathways beneficial for the function, survival and regeneration of pancreatic beta-cells. Additionally, Betacellulin has potential angiogenic activities and is important for the growth, development and repair of certain tissues.Recombinant mouse Betacellulin (rmBetacellulin) produced in E. coli is a single non-glycosylated polypeptide chain containing 81 amino acids. A fully biologically active molecule, rmBetacellulin has a molecular mass of 9.2 kDa analyzed by reducing SDS-PAGE.
Synonyms: BTC - Molecular Weight
- 9.2 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q05928
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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