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CCL16 Protein (AA 24-120)

CCL16 Origin: Human Host: CHO Cells Recombinant > 98 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2017934
  • Target See all CCL16 Proteins
    CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 24-120
    Origin
    Human
    Source
    • 6
    • 1
    • 1
    CHO Cells
    Characteristics
    The EC50 value of human HCC-4/CCL16 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 1.5 μg/mL.
    Purity
    > 98 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product CCL16 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant human HCC4/CCL16 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human HCC4/CCL16 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
    Alternative Name
    HCC-4/CCL16 (CCL16 Products)
    Synonyms
    CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein
    Background
    Human HCC4, also named NCC4and Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). It can signal through the CCR8 and CCR1 receptors, and it is chemotactic towards monocytes and lymphocytes but not neutrophils. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly up-regulated in the presence of IL-10. HCC-4 induces a calcium flux in thp-1 cells that are desensitized prior to the expression of RANTES.
    Synonyms: HCC-4/CCL16, Human
    Molecular Weight
    12 kDa, observed by reducing SDS-PAGE.
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