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IL-3 Protein (AA 27-166) (His tag)

IL-3 Origin: Rat Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018105
  • Target See all IL-3 Proteins
    IL-3 (Interleukin 3 (IL-3))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 27-166
    Origin
    • 22
    • 11
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Source
    • 24
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    CHO Cells
    Purification tag / Conjugate
    This IL-3 protein is labelled with His tag.
    Characteristics
    ED50 < 8 ng/mL, measured in a cell proliferation assay using NF S-60 cells.
    AA 27-166, expressed with C-terminal 6xHis.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product IL-3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant ratInterleukin-3 (IL-3), His remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rat Interleukin-3 (IL-3), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    IL-3 (Interleukin 3 (IL-3))
    Alternative Name
    Interleukin-3 (IL-3) (IL-3 Products)
    Synonyms
    BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
    Background
    Interleukin-3 (IL-3), also known as MCGF, Multi-CSF, HCGF and P-cell stimulation factor, belongs tothe alpha-helixfamily of hematopoietic cytokines. It is produced by activated T-cells, mast cells and natural killer cells. IL-3 binds to the IL-3 receptor alpha subunit and recruits the signal-transducing common beta chain. IL-3induced signal transduction results in the survival, differentiation and proliferation of a variety of immune cells, such as macrophages, neutrophils, megakaryocytes, mast cells and hematopoietic stem cells. IL-3 often acts synergistically with other cytokines, such as IL-7, EPO, GM-CSF and IL-6, to exert its simulative function.
    Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
    Molecular Weight
    22-34 kDa, observed by reducing SDS-PAGE.
    UniProt
    P04823
    Pathways
    JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
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