IL-3 Protein (AA 27-166) (His tag)
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- Target See all IL-3 Proteins
- IL-3 (Interleukin 3 (IL-3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 27-166
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Origin
- Rat
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Source
- CHO Cells
- Purification tag / Conjugate
- This IL-3 protein is labelled with His tag.
- Characteristics
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ED50 < 8 ng/mL, measured in a cell proliferation assay using NF S-60 cells.
AA 27-166, expressed with C-terminal 6xHis. - Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL-3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant ratInterleukin-3 (IL-3), His remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rat Interleukin-3 (IL-3), His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- IL-3 (Interleukin 3 (IL-3))
- Alternative Name
- Interleukin-3 (IL-3) (IL-3 Products)
- Synonyms
- BPA Protein, Csfmu Protein, HCGF Protein, Il-3 Protein, MCGF Protein, PSF Protein, IL-3 Protein, MULTI-CSF Protein, interleukin 3 Protein, interleukin 3 (colony-stimulating factor, multiple) Protein, Il3 Protein, IL3 Protein
- Background
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Interleukin-3 (IL-3), also known as MCGF, Multi-CSF, HCGF and P-cell stimulation factor, belongs tothe alpha-helixfamily of hematopoietic cytokines. It is produced by activated T-cells, mast cells and natural killer cells. IL-3 binds to the IL-3 receptor alpha subunit and recruits the signal-transducing common beta chain. IL-3induced signal transduction results in the survival, differentiation and proliferation of a variety of immune cells, such as macrophages, neutrophils, megakaryocytes, mast cells and hematopoietic stem cells. IL-3 often acts synergistically with other cytokines, such as IL-7, EPO, GM-CSF and IL-6, to exert its simulative function.
Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor - Molecular Weight
- 22-34 kDa, observed by reducing SDS-PAGE.
- UniProt
- P04823
- Pathways
- JAK-STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
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