Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MAG Protein (AA 20-516) (His tag)

MAG Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN2115429
  • Target See all MAG Proteins
    MAG (Myelin Associated Glycoprotein (MAG))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 20-516
    Origin
    • 11
    • 3
    • 3
    Human
    Source
    • 8
    • 5
    • 2
    • 2
    Human Cells
    Purification tag / Conjugate
    This MAG protein is labelled with His tag.
    Purpose
    Recombinant Human Myelin-Associated Glycoprotein/MAG/Siglec-4a (C-6His)
    Sequence
    GHWGAWMPSS ISAFEGTCVS IPCRFDFPDE LRPAVVHGVW YFNSPYPKNY PPVVFKSRTQ VVHESFQGRS RLLGDLGLRN CTLLLSNVSP ELGGKYYFRG DLGGYNQYTF SEHSVLDIVN TPNIVVPPEV VAGTEVEVSC MVPDNCPELR PELSWLGHEG LGEPAVLGRL REDEGTWVQV SLLHFVPTRE ANGHRLGCQA SFPNTTLQFE GYASMDVKYP PVIVEMNSSV EAIEGSHVSL LCGADSNPPP LLTWMRDGTV LREAVAESLL LELEEVTPAE DGVYACLAEN AYGQDNRTVG LSVMYAPWKP TVNGTMVAVE GETVSILCST QSNPDPILTI FKEKQILSTV IYESELQLEL PAVSPEDDGE YWCVAENQYG QRATAFNLSV EFAPVLLLES HCAAARDTVQ CLCVVKSNPE PSVAFELPSR NVTVNESERE FVYSERSGLV LTSILTLRGQ AQAPPRVICT ARNLYGAKSL ELPFQGAHRL MWAKIGPVDH HHHHH
    Characteristics
    Recombinant Human Myelin-Associated Glycoprotein/MAG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gly20-Pro516) of Human MAG fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product MAG Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    MAG (Myelin Associated Glycoprotein (MAG))
    Alternative Name
    MAG (MAG Products)
    Synonyms
    GMA Protein, S-MAG Protein, SIGLEC-4A Protein, SIGLEC4A Protein, siglec-4 Protein, MAG Protein, Gma Protein, siglec-4a Protein, myelin associated glycoprotein Protein, myelin-associated glycoprotein Protein, MAG Protein, mag Protein, Mag Protein
    Background
    Myelin-associated glycoprotein is also known as Siglec-4a, MAG and GMA,is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. MAG is a single-pass type I membrane protein and contains four Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. MAG is a adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. MAG is a functional ligand of the NOGO-66 receptor. MAG is thought be involved in myelination during nerve regeneration.
    Synonyms: Myelin-Associated Glycoprotein, Siglec-4a, MAG, GMA
    Molecular Weight
    55.7 kDa
    UniProt
    P20916
    Pathways
    Neurotrophin Signaling Pathway
You are here:
Support