FZD7 Protein (AA 33-185) (Fc Tag)
FZD7
Origin: Human
Host: HEK-293 Cells
Recombinant
>92 % as determined by SDS-PAGE.
1 image
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- Target See all FZD7 products
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-185
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FZD7 protein is labelled with Fc Tag.
- Sequence
- AA 33-185
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 43.3 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >92 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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Frizzled Family Receptor 7 (FZD7) (AA 155-253) protein (GST tag)
FZD7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 7 (FZD7) (AA 1-574) protein (GST tag)FZD7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Alternative Name
- Frizzled-7 (FZD7 Products)
- Synonyms
- FzE3 Protein, Fz-7 Protein, Xfz7 Protein, frizzled-7 Protein, frizzled7 Protein, frz-7 Protein, frz7 Protein, fz7 Protein, fzd7-a Protein, fzd7-b Protein, fze3 Protein, Fz7 Protein, cFz-7 Protein, fb38g02 Protein, fc44b09 Protein, fz13 Protein, fz7a Protein, fz7b Protein, wu:fb38g02 Protein, wu:fc44b09 Protein, zg13 Protein, frizzled class receptor 7 Protein, frizzled class receptor 7 L homeolog Protein, frizzled class receptor 7b Protein, FZD7 Protein, fzd7.L Protein, fzd7 Protein, Fzd7 Protein, fzd7b Protein
- Background
- Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.
- Molecular Weight
- 43.3 kDa
- Pathways
- WNT Signaling, Stem Cell Maintenance
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