FZD7 Protein (Fc Tag,His tag)
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- Target See all FZD7 products
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FZD7 protein is labelled with Fc Tag,His tag.
- Purpose
- Active Recombinant Human Frizzled-7/FZD7 Protein
- Sequence
- QPYHGEKGIS VPDHGFCQPI SIPLCTDIAY NQTILPNLLG HTNQEDAGLE VHQFYPLVKV QCSPELRFFL CSMYAPVCTV LDQAIPPCRS LCERARQGCE ALMNKFGFQW PERLRCENFP VHGAGEICVG QNTSDGSGGP GGGPTAYPTA PYL
- Specificity
- Gln33-Leu185
- Purity
- > 95 % by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- 1.Measured by its binding ability in a functional ELISA. Immobilized Human Glypican-3 Protein at 5 μg/mL (100 μL/well) can bind Human FZD7 with a linear range of 4.88-935.5 ng/mL.|2.Measured by its binding ability in a functional ELISA. Immobilized Human Glypican-3 Protein at 5 μg/mL (100 μL/well) can bind Human FZD7 with a linear range of 4.88-520.4 ng/mL.
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Frizzled Family Receptor 7 (FZD7) (AA 155-253) protein (GST tag)
FZD7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 7 (FZD7) (AA 1-574) protein (GST tag)FZD7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Frizzled Family Receptor 7 (FZD7) (AA 33-185) protein (Fc Tag)FZD7 Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C,-80 °C
- Storage Comment
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Target
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Alternative Name
- Frizzled-7/FZD7 (FZD7 Products)
- Synonyms
- FzE3 Protein, Fz-7 Protein, Xfz7 Protein, frizzled-7 Protein, frizzled7 Protein, frz-7 Protein, frz7 Protein, fz7 Protein, fzd7-a Protein, fzd7-b Protein, fze3 Protein, Fz7 Protein, cFz-7 Protein, fb38g02 Protein, fc44b09 Protein, fz13 Protein, fz7a Protein, fz7b Protein, wu:fb38g02 Protein, wu:fc44b09 Protein, zg13 Protein, frizzled class receptor 7 Protein, frizzled class receptor 7 L homeolog Protein, frizzled class receptor 7b Protein, FZD7 Protein, fzd7.L Protein, fzd7 Protein, Fzd7 Protein, fzd7b Protein
- Background
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Description: Frizzled-7 is a member of the Frizzled family of unconventional G-protein-coupled glycoprotein receptors for the Wnt signaling pathway. During development, Frizzled-7 is expressed during gastrulation and in the fetal gut, kidney and lung where it is thought to influence tissue morphogenesis via non-canonical signaling pathways . In the adult, Frizzled-7 is expressed in skeletal muscle, especially in satellite cells that mediate muscle regeneration in response to Wnt-7a. It is expressed in embryonic stem cells (ES), contributing to self-renewal signaling . Frizzled-7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Name: FZD7,FzE3
- Gene ID
- 8324
- UniProt
- O75084
- Pathways
- WNT Signaling, Stem Cell Maintenance
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