FGF4 Protein
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- Target See all FGF4 Proteins
- FGF4 (Fibroblast Growth Factor 4 (FGF4))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
- Characteristics
- The ED50 was determined by the dose - dependent stimulation of thymidine uptake by BaF3 cells expressing FGF - receptors is < 0.5 ng/mL, corresponding to a specific activity of > 2 x 106 units/mg.
- Purity
- < 95 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin Level
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product FGF4 Protein
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Fibroblast Growth Factor 4 (FGF4) (AA 71-206) protein (His tag)
FGF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibroblast Growth Factor 4 (FGF4) (AA 25-206) protein (His tag)FGF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 4 (FGF4) proteinFGF4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Handling Advice
- As with any protein, exposing FGF-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -20 °C
- Storage Comment
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted FGF-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Expiry Date
- 24 months
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- Target
- FGF4 (Fibroblast Growth Factor 4 (FGF4))
- Alternative Name
- FGF-4 (FGF4 Products)
- Synonyms
- HBGF-4 Protein, HST Protein, HST-1 Protein, HSTF1 Protein, K-FGF Protein, KFGF Protein, Fgf-4 Protein, Fgfk Protein, Hst1 Protein, Hstf-1 Protein, KS3 Protein, hst Protein, hst-1 Protein, kFGF Protein, Hst Protein, fibroblast growth factor 4 Protein, FGF4 Protein, Fgf4 Protein
- Background
- FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.
- Gene ID
- 2249
- NCBI Accession
- NP_001998
- OMIM
- 4503701
- UniProt
- P08620
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance
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