NLRP1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
NLRP1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
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- Target See all NLRP1 products
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NLRP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CARD7 / NLRP1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
- Alternative Name
- Card7,nlrp1 (NLRP1 Products)
- Synonyms
- CARD7 Protein, CIDED Protein, CLR17.1 Protein, DEFCAP Protein, DEFCAP-L/S Protein, NAC Protein, NALP1 Protein, PP1044 Protein, SLEV1 Protein, VAMAS1 Protein, NLR family pyrin domain containing 1 Protein, NLRP1 Protein, Nlrp1 Protein
- Background
- This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
- Molecular Weight
- 165.7 kDa
- NCBI Accession
- NP_127497
- Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
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