TEK Protein (DYKDDDDK-His Tag)
Quick Overview for TEK Protein (DYKDDDDK-His Tag) (ABIN2713497)
Target
See all TEK ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TEK protein is labelled with DYKDDDDK-His Tag.
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Characteristics
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- Recombinant human CD202b / TEK (C-term DDK/His tag) protein expressed in Human 293HEK cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 1 x PBS, pH 7.4, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Alternative Name
- Cd202b,tek
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Background
- This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Molecular Weight
- 84 kDa
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NCBI Accession
- NP_000450
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Pathways
- RTK Signaling, Growth Factor Binding
Target
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