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TEK Protein (Fc Tag)

TEK Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN6964382
  • Target See all TEK Proteins
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Protein Type
    Recombinant
    Origin
    • 20
    • 11
    • 3
    • 2
    • 2
    • 1
    Human
    Source
    • 10
    • 10
    • 10
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This TEK protein is labelled with Fc Tag.
    Sequence
    TIE2 (Trp23-Leu748)+hFc(GLU99-ALA330)
    Characteristics
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
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    Discover our top product TEK Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -80 °C
    Storage Comment
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Expiry Date
    12 months
  • Target
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    Alternative Name
    TIE2 (TEK Products)
    Synonyms
    TEK Protein, DKFZp469E064 Protein, AA517024 Protein, Cd202b Protein, Hyk Protein, Tie2 Protein, tie-2 Protein, CD202B Protein, TIE-2 Protein, TIE2 Protein, VMCM Protein, VMCM1 Protein, Tie-2 Protein, tie2 Protein, TEK receptor tyrosine kinase Protein, angiopoietin-1 receptor Protein, TEK tyrosine kinase, endothelial Protein, TEK Protein, LOC100408334 Protein, tek Protein, Tek Protein
    Background
    Synonymes: CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
    Description: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
    Molecular Weight
    105.38 kDa
    UniProt
    Q02763
    Pathways
    RTK Signaling, Growth Factor Binding
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