TEK Protein (Fc Tag)
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- Target See all TEK Proteins
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TEK protein is labelled with Fc Tag.
- Sequence
- TIE2 (Trp23-Leu748)+hFc(GLU99-ALA330)
- Characteristics
- Tagged Protein: C-Human Fc tag
- Purification
- affinity purification
- Top Product
- Discover our top product TEK Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Preservative
- Without preservative
- Storage
- -80 °C
- Storage Comment
- Store at -80°C for 12 months (Avoid repeated freezing and thawing)
- Expiry Date
- 12 months
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- Target
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- Alternative Name
- TIE2 (TEK Products)
- Synonyms
- TEK Protein, DKFZp469E064 Protein, AA517024 Protein, Cd202b Protein, Hyk Protein, Tie2 Protein, tie-2 Protein, CD202B Protein, TIE-2 Protein, TIE2 Protein, VMCM Protein, VMCM1 Protein, Tie-2 Protein, tie2 Protein, TEK receptor tyrosine kinase Protein, angiopoietin-1 receptor Protein, TEK tyrosine kinase, endothelial Protein, TEK Protein, LOC100408334 Protein, tek Protein, Tek Protein
- Background
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Synonymes: CD202B, GLC3E, TIE-2, TIE2, VMCM, VMCM1
Description: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014] - Molecular Weight
- 105.38 kDa
- UniProt
- Q02763
- Pathways
- RTK Signaling, Growth Factor Binding
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