CDK8 Protein (Myc-DYKDDDDK Tag)
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- Target See all CDK8 Proteins
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CDK8 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CDK8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CDK8 Protein
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Cyclin-Dependent Kinase 8 (CDK8) (AA 1-464) (Active) protein (GST tag)
CDK8 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Cyclin-Dependent Kinase 8 (CDK8) (AA 1-464) (Active) protein (His tag)CDK8 Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Cyclin-Dependent Kinase 8 (CDK8) (AA 375-464) protein (GST tag)CDK8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 8 (CDK8) (AA 1-464) protein (Strep Tag)Crystallography grade CDK8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Cyclin-Dependent Kinase 8 (CDK8) (AA 1-464) protein (Strep Tag)Crystallography grade CDK8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- Alternative Name
- Cdk8 (CDK8 Products)
- Synonyms
- K35 Protein, wu:fk95h11 Protein, cyclin dependent kinase 8 Protein, cyclin-dependent kinase 8 Protein, cyclin-dependent kinase 8 S homeolog Protein, Cyclin-dependent kinase 8 Protein, cyclin dependent kinase 19 Protein, CDK8 Protein, Cdk8 Protein, cdk8 Protein, cdk8.S Protein, cdk-8 Protein, CDK19 Protein
- Background
- This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 53.1 kDa
- NCBI Accession
- NP_001251
- Pathways
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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