GM2A Protein (Myc-DYKDDDDK Tag)
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- Target See all GM2A Proteins
- GM2A (GM2 Ganglioside Activator (GM2A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GM2A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GM2A / SAP3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GM2A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GM2A (GM2 Ganglioside Activator (GM2A))
- Alternative Name
- Gm2a,sap3 (GM2A Products)
- Synonyms
- GM2A Protein, fb96e04 Protein, fb96e10 Protein, wu:fb96e04 Protein, wu:fb96e10 Protein, zgc:110188 Protein, MGC84154 Protein, GM2-AP Protein, SAP-3 Protein, AA408702 Protein, AW215435 Protein, GM2 ganglioside activator Protein, GM2 ganglioside activator L homeolog Protein, GM2 ganglioside activator protein Protein, Gm2a Protein, GM2A Protein, gm2a Protein, gm2a.L Protein
- Background
- This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 20.7 kDa
- NCBI Accession
- NP_000396
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