HDAC3 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2722499

Product Details

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HDAC3 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human HDAC3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Alternative Name: Hdac3 (HDAC3 Products)

Synonyms: CG2128 Protein, DHDAC3 Protein, DmHDAC3 Protein, Dmel\\CG2128 Protein, Dromel_CG2128_FBtr0078767_hdac3_mORF Protein, HDAC Protein, HDAC3 Protein, Hdac 3 Protein, dHDAC3 Protein, dmHDA402 Protein, hdac3 Protein, HDm Protein, hd3 Protein, RPD3 Protein, XRpd3 Protein, rpd3-2 Protein, HD3 Protein, RPD3-2 Protein, AW537363 Protein, zgc:55927 Protein, Histone deacetylase 3 Protein, histone deacetylase 3 Protein, histone deacetylase 3 S homeolog Protein, HDAC3 Protein, hdac3 Protein, CNL05260 Protein, Hdac3 Protein, hdac3.S Protein

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Molecular Weight: 48.7 kDa

NCBI Accession: NP_003874

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development