JUP Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
-
- Target See all JUP Proteins
- JUP (Junction Plakoglobin (JUP))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JUP protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human Junction plakoglobin (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product JUP Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- JUP (Junction Plakoglobin (JUP))
- Alternative Name
- Junction Plakoglobin (JUP Products)
- Synonyms
- ARVD12 Protein, CTNNG Protein, DP3 Protein, DPIII Protein, PDGB Protein, PKGB Protein, arvd12 Protein, ctnng Protein, dp3 Protein, dpiii Protein, pdgb Protein, pkgb Protein, plak Protein, D930025P04Rik Protein, PG Protein, cb80 Protein, danPG Protein, fb11b06 Protein, jup Protein, wu:fb11b06 Protein, junction plakoglobin Protein, junction plakoglobin L homeolog Protein, Junction plakoglobin Protein, junction plakoglobin a Protein, junction plakoglobin S homeolog Protein, JUP Protein, Jup Protein, jup Protein, jup.L Protein, Tsp_06656 Protein, plak Protein, jupa Protein, jup.S Protein
- Background
- This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene however, not all transcripts have been fully described.
- Molecular Weight
- 81.6 kDa
- NCBI Accession
- NP_002221
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
-