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KCNQ4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

KCNQ4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724049
  • Target See all KCNQ4 Proteins
    KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 3
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This KCNQ4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human KCNQ4 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KCNQ4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
    Alternative Name
    Kcnq4 (KCNQ4 Products)
    Synonyms
    KCNQ4 Protein, k(v)7.4 Protein, kv7.4 Protein, DFNA2 Protein, DFNA2A Protein, KV7.4 Protein, potassium voltage-gated channel subfamily Q member 4 Protein, potassium channel, voltage gated KQT-like subfamily Q, member 4 Protein, potassium voltage-gated channel, subfamily Q, member 4 Protein, KCNQ4 Protein, kcnq4 Protein, Kcnq4 Protein
    Background
    Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    71 kDa
    NCBI Accession
    NP_751895
    Pathways
    Sensory Perception of Sound
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