MAP3K1 Protein (Myc-DYKDDDDK Tag)
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- Target See all MAP3K1 Proteins
- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MAP3K1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MAP3K1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MAP3K1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))
- Alternative Name
- Map3k1 (MAP3K1 Products)
- Synonyms
- MAP3K1 Protein, Mekk1 Protein, MAPKKK1 Protein, MEKK1 Protein, Mekk Protein, ARAKIN Protein, ATMEKK1 Protein, MAPK/ERK kinase kinase 1 Protein, MAPKKK8 Protein, T15F16.5 Protein, T15F16_5 Protein, MEKK Protein, MEKK 1 Protein, SRXY6 Protein, mitogen-activated protein kinase kinase kinase 1 Protein, mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase Protein, MAPK/ERK kinase kinase 1 Protein, MAP3K1 Protein, map3k1 Protein, Map3k1 Protein, MEKK1 Protein
- Background
- The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus.
- Molecular Weight
- 164.3 kDa
- NCBI Accession
- NP_005912
- Pathways
- MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades
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