CCL28 Protein

Catalog No. ABIN2725722

Product Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)

Specificity: Optimal preservation of protein structure, post-translational modifications and functions.

Characteristics:

• Recombinant human MEC / CCL28 protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Handling

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handling Advice: Resuspend the protein in the desired concentration in proper buffer

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CCL28 (Chemokine (C-C Motif) Ligand 28 (CCL28))

Alternative Name: Mec,ccl28 (CCL28 Products)

Synonyms: Scya28 Protein, CCL28 Protein, ccl28 Protein, nrpb Protein, enc-1 Protein, pig10 Protein, Encr-3 Protein, klhl35 Protein, Xencr-3 Protein, tp53i10 Protein, LOC100303767 Protein, CCK1 Protein, MEC Protein, SCYA28 Protein, C-C motif chemokine ligand 28 Protein, ectodermal-neural cortex 1 (with BTB domain) Protein, C-C motif chemokine 28 Protein, chemokine (C-C motif) ligand 28 Protein, Ccl28 Protein, CCL28 Protein, ccl28 Protein, enc1 Protein, LOC100303767 Protein

Background: This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. Multiple transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 12.3 kDa

NCBI Accession: NP_683513