MUS81 Protein (Myc-DYKDDDDK Tag)
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- Target See all MUS81 Proteins
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MUS81 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MUS81 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MUS81 Protein
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MUS81 Endonuclease Homolog (MUS81) (AA 452-549) protein (GST tag)
MUS81 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
MUS81 Endonuclease Homolog (MUS81) (AA 1-551) protein (GST tag)MUS81 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
MUS81 Endonuclease Homolog (MUS81) (AA 1-551) protein (Strep Tag)Crystallography grade MUS81 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
MUS81 Endonuclease Homolog (MUS81) (AA 1-551) protein (Strep Tag)Crystallography grade MUS81 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
- Alternative Name
- Mus81 (MUS81 Products)
- Synonyms
- CG3026 Protein, Dmel\\CG3026 Protein, EG:BACR7A4.16 Protein, MUS81 Protein, GB15332 Protein, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 Protein, ATMUS81 Protein, F6I18.220 Protein, F6I18_220 Protein, MMS AND UV SENSITIVE 81 Protein, SLX3 Protein, slx3 Protein, 1200008A18Rik Protein, AI182501 Protein, AW045863 Protein, wu:fc26g01 Protein, zgc:66489 Protein, zgc:91801 Protein, CG3026 gene product from transcript CG3026-RA Protein, MUS81 structure-specific endonuclease subunit Protein, crossover junction endonuclease MUS81 Protein, Restriction endonuclease, type II-like superfamily protein Protein, Mus81p Protein, Holliday junction resolvase subunit Mus81 Protein, MUS81 protein Protein, hypothetical protein Protein, mus81 Protein, MUS81 Protein, LOC725951 Protein, Mus81 Protein, CAALFM_C600540WA Protein
- Background
- This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after interstrand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
- Molecular Weight
- 61 kDa
- NCBI Accession
- NP_079404
- Pathways
- DNA Damage Repair
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