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MUS81 Products

(MUS81 Endonuclease Homolog (MUS81))

Categories

Interacts with EME1 and EME2 to form a DNA structure- specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

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Featured MUS81 Categories

MUS81 Antibodies

High quality antibodies with extensive validation data.

MUS81 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MUS81 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7148695
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN6144202
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7262745
Quantity 200 μL
Datasheet Datasheet

Recommended MUS81 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311657
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1311656
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093974
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MUS81 products

Sun, Brieño-Enríquez, Cornelius, Modzelewski, Maley, Campbell-Peterson, Holloway, Cohen: "FancJ (Brip1) loss-of-function allele results in spermatogonial cell depletion during embryogenesis and altered processing of crossover sites during meiotic prophase I in mice." in: Chromosoma, Vol. 125, Issue 2, pp. 237-52, (2016) (PubMed).

Benitez, Yuan, Nakajima, Wei, Qian, Myers, Hu, Lan, Zhang: "Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein." in: Nucleic acids research, Vol. 42, Issue 3, pp. 1671-83, (2014) (PubMed).

Rodrigue, Coulombe, Jacquet, Gagné, Roques, Gobeil, Poirier, Masson: "The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy." in: Journal of cell science, Vol. 126, Issue Pt 1, pp. 348-59, (2013) (PubMed).

Murfuni, De Santis, Federico, Bignami, Pichierri, Franchitto: "Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN." in: Carcinogenesis, Vol. 33, Issue 9, pp. 1655-63, (2012) (PubMed).

Duquette, Zhu, Taylor, Tsay, Shi, Berns, McGowan: "CtIP is required to initiate replication-dependent interstrand crosslink repair." in: PLoS genetics, Vol. 8, Issue 11, pp. e1003050, (2012) (PubMed).

Domínguez-Kelly, Martín, Koundrioukoff, Tanenbaum, Smits, Medema, Debatisse, Freire: "Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease." in: The Journal of cell biology, Vol. 194, Issue 4, pp. 567-79, (2011) (PubMed).

Regairaz, Zhang, Fu, Agama, Tata, Agrawal, Aladjem, Pommier: "Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes." in: The Journal of cell biology, Vol. 195, Issue 5, pp. 739-49, (2011) (PubMed).

Stoepker, Hain, Schuster, Hilhorst-Hofstee, Rooimans, Steltenpool, Oostra, Eirich, Korthof, Nieuwint, Jaspers, Bettecken, Joenje, Schindler, Rouse, de Winter: "SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype." in: Nature genetics, Vol. 43, Issue 2, pp. 138-41, (2011) (PubMed).

Rass, Compton, Matos, Singleton, Ip, Blanco, Griffith, West: "Mechanism of Holliday junction resolution by the human GEN1 protein." in: Genes & development, Vol. 24, Issue 14, pp. 1559-69, (2010) (PubMed).

Zeng, Xiang, Pandita, Gonzalez-Suarez, Gonzalo, Harris, Yang: "Telomere recombination requires the MUS81 endonuclease." in: Nature cell biology, Vol. 11, Issue 5, pp. 616-23, (2009) (PubMed).

Synonyms and alternative names related to MUS81

CG3026 gene product from transcript CG3026-RA (mus81), MUS81 structure-specific endonuclease subunit (MUS81), MUS81 structure-specific endonuclease subunit (mus81), crossover junction endonuclease MUS81 (LOC725951), Restriction endonuclease, type II-like superfamily protein (MUS81), Mus81p (MUS81), Holliday junction resolvase subunit Mus81 (mus81), MUS81 protein (mus81), MUS81 structure-specific endonuclease subunit (Mus81), hypothetical protein (CAALFM_C600540WA), 1200008A18Rik, AI182501, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81, ATMUS81, AW045863, CG3026, Dmel\\CG3026, EG:BACR7A4.16, F6I18.220, F6I18_220, GB15332, MMS AND UV SENSITIVE 81, MUS81, SLX3, slx3, wu:fc26g01, zgc:66489, zgc:91801

Protein level used designations for MUS81

  • CG3026-PA
  • mus81-PA
  • crossover junction endonuclease MUS81
  • MUS81 endonuclease homolog (S. cerevisiae)
  • MUS81 endonuclease homolog
  • MUS81 protein
  • crossover junction endonuclease MUS81-like
  • SLX3 structure-specific endonuclease subunit homolog
  • hypothetical protein
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