MUTYH Protein (His tag)
-
- Target See all MUTYH Proteins
- MUTYH (MutY Homolog (E. Coli) (MUTYH))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MUTYH protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human MUTYH (full length, N-term HIS tag, transcript variant alpha1) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MUTYH Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the N-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- MUTYH (MutY Homolog (E. Coli) (MUTYH))
- Alternative Name
- Mutyh (MUTYH Products)
- Synonyms
- MUTYH Protein, MGC145569 Protein, CYP2C Protein, MYH Protein, 5730495A01Rik Protein, Mutyha Protein, Mutyhalpha Protein, Mutyhb Protein, Mutyhbeta Protein, Mutyhc Protein, Myh Protein, mutY DNA glycosylase Protein, mutY homolog (E. coli) Protein, A/G-specific adenine DNA glycosylase-like Protein, MUTYH Protein, mutyh Protein, LOC100373318 Protein, Mutyh Protein
- Background
- This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 59.9 kDa
- NCBI Accession
- NP_036354
- Pathways
- DNA Damage Repair
-