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MUTYH Protein (His tag)

MUTYH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2726612
  • Target See all MUTYH Proteins
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MUTYH protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MUTYH (full length, N-term HIS tag, transcript variant alpha1) protein expressed in E.coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MUTYH Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    Alternative Name
    Mutyh (MUTYH Products)
    Synonyms
    MUTYH Protein, MGC145569 Protein, CYP2C Protein, MYH Protein, 5730495A01Rik Protein, Mutyha Protein, Mutyhalpha Protein, Mutyhb Protein, Mutyhbeta Protein, Mutyhc Protein, Myh Protein, mutY DNA glycosylase Protein, mutY homolog (E. coli) Protein, A/G-specific adenine DNA glycosylase-like Protein, MUTYH Protein, mutyh Protein, LOC100373318 Protein, Mutyh Protein
    Background
    This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    59.9 kDa
    NCBI Accession
    NP_036354
    Pathways
    DNA Damage Repair
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