NFKBIA Protein (Myc-DYKDDDDK Tag)
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- Target See all NFKBIA Proteins
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NFKBIA protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NFKBIA / IKBA protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NFKBIA Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
- Alternative Name
- Nfkbia,ikba (NFKBIA Products)
- Synonyms
- IKBA Protein, MAD-3 Protein, NFKBI Protein, AI462015 Protein, Nfkbi Protein, RL/IF-1 Protein, ECI-6/IKBA Protein, NFKBIA Protein, ikbaB Protein, wu:fb81f08 Protein, zgc:56666 Protein, zgc:77616 Protein, ikbaA Protein, wu:fj16a07 Protein, zgc:85769 Protein, NFKB inhibitor alpha Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a Protein, NFKBIA Protein, Nfkbia Protein, nfkbiab Protein, nfkbiaa Protein
- Background
- This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
- Molecular Weight
- 35.4 kDa
- NCBI Accession
- NP_065390
- Pathways
- NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling
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