RAB8A Protein (Myc-DYKDDDDK Tag)
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- Target See all RAB8A Proteins
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RAB8A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RAB8A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAB8A Protein
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RAB8A, Member RAS Oncogene Family (RAB8A) (AA 1-207) protein (GST tag)
RAB8A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
RAB8A, Member RAS Oncogene Family (RAB8A) (AA 108-207) protein (GST tag)RAB8A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
RAB8A, Member RAS Oncogene Family (RAB8A) (AA 1-204) protein (His tag)Crystallography grade RAB8A Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
RAB8A, Member RAS Oncogene Family (RAB8A) (AA 1-204) protein (His tag)Crystallography grade RAB8A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
- Alternative Name
- Rab8a (RAB8A Products)
- Synonyms
- rab8A Protein, DDBDRAFT_0206521 Protein, DDBDRAFT_0214885 Protein, DDB_0206521 Protein, DDB_0214885 Protein, HSH2D Protein, mel Protein, rab8 Protein, c-mel Protein, MEL Protein, RAB8 Protein, zgc:162699 Protein, AA409338 Protein, Mel Protein, Rab8 Protein, rab8A protein Protein, Rab GTPase Protein, RAB8A, member RAS oncogene family Protein, RAB8A, member RAS oncogene family S homeolog Protein, rab8A Protein, RAB8A Protein, rab8a Protein, rab8a.S Protein, Rab8a Protein
- Background
- The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
- Molecular Weight
- 23.5 kDa
- NCBI Accession
- NP_005361
- Pathways
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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