RIPK3 Protein (GST tag)
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- Target See all RIPK3 Proteins
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Insect cells (Sf9)
- Purification tag / Conjugate
- This RIPK3 protein is labelled with GST tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RIPK3 / RIP3 (full length, N-term GST tag, C-term His tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RIPK3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris-HCl, pH 7.4, 20 mM Imidazole, 0.3 mM DTT, 10 % glycerol
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- Alternative Name
- Ripk3,rip3 (RIPK3 Products)
- Synonyms
- RIPK3 Protein, RIP3 Protein, 2610528K09Rik Protein, AW107945 Protein, Rip3 Protein, Hcyp2 Protein, receptor interacting serine/threonine kinase 3 Protein, receptor interacting serine/threonine kinase 3 S homeolog Protein, receptor-interacting serine-threonine kinase 3 Protein, RIPK3 Protein, ripk3.S Protein, Ripk3 Protein
- Background
- The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
- Molecular Weight
- 56.7 kDa
- NCBI Accession
- NP_006862
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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