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FDFT1 Protein (Myc-DYKDDDDK Tag)

FDFT1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732647
  • Target See all FDFT1 Proteins
    FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 3
    • 2
    Human
    Source
    • 6
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FDFT1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Squalene synthetase protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FDFT1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
    Alternative Name
    Squalene Synthetase (FDFT1 Products)
    Synonyms
    FDFT1 Protein, DKFZp459C1712 Protein, SQS Protein, SS Protein, DGPT Protein, ERG9 Protein, fdft1 Protein, farnesyl-diphosphate farnesyltransferase 1 Protein, squalene synthase Protein, farnesyl diphosphate farnesyl transferase 1 Protein, FDFT1 Protein, fdft1 Protein, LOC100560926 Protein, Fdft1 Protein
    Background
    This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
    Molecular Weight
    47.9 kDa
    NCBI Accession
    NP_004453
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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