JAK3 Protein (Myc-DYKDDDDK Tag)
-
- Target See all JAK3 Proteins
- JAK3 (Janus Kinase 3 (JAK3))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This JAK3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human Tyrosine-protein kinase JAK3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product JAK3 Protein
-
Janus Kinase 3 (JAK3) (AA 795-1124) (Active) protein (GST tag)
JAK3 Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 3 (JAK3) (AA 781-1124) (Active) protein (His-GST)JAK3 Origin: Human Host: Insect cells (Sf9) Recombinant SDS, Func Active
Janus Kinase 3 (JAK3) (AA 1-619) protein (GST tag)JAK3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Janus Kinase 3 (JAK3) (AA 1-1124) protein (Strep Tag)Crystallography grade JAK3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Janus Kinase 3 (JAK3) (AA 1-1100) protein (Strep Tag)Crystallography grade JAK3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Janus Kinase 3 (JAK3) (AA 818-110) protein (His tag)JAK3 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- JAK3 (Janus Kinase 3 (JAK3))
- Alternative Name
- Tyrosine-Protein Kinase Jak3 (JAK3 Products)
- Synonyms
- JAK-3 Protein, JAK3_HUMAN Protein, JAKL Protein, L-JAK Protein, LJAK Protein, fae Protein, wil Protein, RATJAK3 Protein, JAK Protein, Janus kinase 3 Protein, JAK3 Protein, Jak3 Protein
- Background
- The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
- Molecular Weight
- 124.9 kDa
- NCBI Accession
- NP_000206
- Pathways
- JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
-
