XRCC4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all XRCC4 Proteins
- XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This XRCC4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human XRCC4 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product XRCC4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- XRCC4 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
- Alternative Name
- Xrcc4 (XRCC4 Products)
- Synonyms
- zgc:73312 Protein, MGC81443 Protein, homolog of human DNA ligase iv-binding protein XRCC4 Protein, 2310057B22Rik Protein, AW413319 Protein, AW545101 Protein, X-ray repair cross complementing 4 Protein, X-ray repair complementing defective repair in Chinese hamster cells 4 Protein, X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog Protein, DNA ligase IV-binding protein Protein, XRCC4 Protein, xrcc4 Protein, xrcc4.L Protein, Xrcc4 Protein
- Background
- The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.
- Molecular Weight
- 37.9 kDa
- NCBI Accession
- NP_003392
- Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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