APEX1 Protein (AA 2-318)
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- Target See all APEX1 Proteins
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-318
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS), Western Blotting (WB), ELISA, Mass Spectrometry (MS)
- Purpose
- Recombinant Human APEX1 Protein is produced by our E.coli expression system and the target gene encoding Pro2-Leu318 is expressed.
- Sequence
- MGPKRGKKGA VAEDGDELRT EPEAKKSKTA AKKNDKEAAG EGPALYEDPP DQKTSPSGKP ATLKICSWNV DGLRAWIKKK GLDWVKEEAP DILCLQETKC SENKLPAELQ ELPGLSHQYW SAPSDKEGYS GVGLLSRQCP LKVSYGIGEE EHDQEGRVIV AEFDSFVLVT AYVPNAGRGL VRLEYRQRWD EAFRKFLKGL ASRKPLVLCG DLNVAHEEID LRNPKGNKKN AGFTPQERQG FGELLQAVPL ADSFRHLYPN TPYAYTFWTY MMNARSKNVG WRLDYFLLSH SLLPALCDSK IRSKALGSDH CPITLYLAL
- Purity
- Greater than 95 % as determined by SEC-HPLC and reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
- Top Product
- Discover our top product APEX1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as a 0.2 μM filtered solution of 10 mM HEPES, 100 mM KCl, 50 % Glycerol, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
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- Target
- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
- Alternative Name
- APEX1 (APEX1 Products)
- Synonyms
- apex1 Protein, MGC76280 Protein, MGC79645 Protein, MGC78928 Protein, APE Protein, APE1 Protein, APEN Protein, APEX Protein, APX Protein, HAP1 Protein, REF1 Protein, Apex Protein, REF-1 Protein, BAP1 Protein, apex1a Protein, hm:zehn1532 Protein, wu:fc13d11 Protein, zgc:66204 Protein, Ref-1 Protein, apurinic/apyrimidinic endodeoxyribonuclease 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 Protein, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog Protein, DNA-(apurinic or apyrimidinic site) lyase Protein, apurinic/apyrimidinic endonuclease 1 Protein, APEX1 Protein, apex1 Protein, apex1.L Protein, CNG03640 Protein, CNH01280 Protein, nth Protein, Spirs_4119 Protein, Palpr_0103 Protein, Apex1 Protein
- Gene ID
- 328
- UniProt
- P27695
- Pathways
- DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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