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BTN1A1 Protein (AA 27-242) (Fc Tag)

BTN1A1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func
Catalog No. ABIN4949082
  • Target See all BTN1A1 Proteins
    BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-242
    Origin
    • 20
    • 5
    • 1
    Human
    Source
    • 10
    • 6
    • 5
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This BTN1A1 protein is labelled with Fc Tag.
    Application
    Functional Studies (Func)
    Sequence
    AA 27-242
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE).
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
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    Discover our top product BTN1A1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
  • Target
    BTN1A1 (Butyrophilin, Subfamily 1, Member A1 (BTN1A1))
    Alternative Name
    BTN1A1 (BTN1A1 Products)
    Synonyms
    BT Protein, BTN Protein, Btn Protein, BTN1A1 Protein, TVC Protein, butyrophilin subfamily 1 member A1 Protein, butyrophilin, subfamily 1, member A1 Protein, zgc:162154 Protein, BTN1A1 Protein, Btn1a1 Protein, btn1a1 Protein, zgc:162154 Protein
    Background
    Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
    Molecular Weight
    50.6 kDa
    Pathways
    Activated T Cell Proliferation
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