Mre11 Protein (His tag)
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- Target See all Mre11 (MRE11A) Proteins
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Mre11 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Purified recombinant protein of Human MRE11 meiotic recombination 11 homolog A (S. cerevisiae) (MRE11A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purification
- Purified
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MRE11A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Alternative Name
- MRE11 meiotic recombination 11 homolog A (MRE11A Products)
- Synonyms
- wu:faa63d12 Protein, zgc:64018 Protein, Mre11 Protein, Mre11b Protein, ATLD Protein, HNGS1 Protein, MRE11 Protein, MRE11B Protein, MRE11 homolog A, double strand break repair nuclease Protein, MRE11 homolog, double strand break repair nuclease Protein, MRE11A homolog A, double strand break repair nuclease Protein, mre11a Protein, MRE11 Protein, Mre11a Protein
- Background
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3&apos to 5&apos exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3&apos to 5&apos exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Molecular Weight
- 77.5 kDa
- NCBI Accession
- NP_005581
- Pathways
- DNA Damage Repair
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