A2BP1 Protein (His tag)
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- Target See all A2BP1 Proteins
- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This A2BP1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Purified recombinant protein of Human RNA binding protein, fox-1 homolog (C. elegans) 1 (RBFOX1), transcript variant 6, full length, with N-terminal HIS tag, expressed in E. coli, 50 μg (full length, N-term HIS tag, transcript variant 6) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purification
- Purified
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product A2BP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
- Alternative Name
- RBFOX1 (A2BP1 Products)
- Synonyms
- A2BP1 Protein, fox1 Protein, a2bp1 Protein, zgc:103635 Protein, 2BP1 Protein, FOX-1 Protein, FOX1 Protein, HRNBP1 Protein, A2bp Protein, A2bp1 Protein, Hrnbp1 Protein, fox-1 Protein, RNA binding protein, fox-1 homolog 1 Protein, RNA binding fox-1 homolog 1 Protein, multicopper ferroxidase Protein, RNA binding protein, fox-1 homolog (C. elegans) 1 Protein, RBFOX1 Protein, rbfox1 Protein, FOX1 Protein, Rbfox1 Protein
- Background
- The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 42.6 kDa
- NCBI Accession
- NP_001135806
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