CTHRC1 Protein (AA 33-245) (DYKDDDDK Tag)
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- Target See all CTHRC1 Proteins
- CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-245
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Origin
- Mouse
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Source
- CHO Cells
- Purification tag / Conjugate
- This CTHRC1 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse CTHRC1 (aa 33-245) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product CTHRC1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Solid
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))
- Alternative Name
- CTHRC1 (CTHRC1 Products)
- Synonyms
- CTHRC1 Protein, cthrc1 Protein, zgc:101075 Protein, 1110014B07Rik Protein, collagen triple helix repeat containing 1 Protein, collagen triple helix repeat containing 1a Protein, CTHRC1 Protein, cthrc1 Protein, cthrc1a Protein, Cthrc1 Protein
- Background
- Collagen triple helix repeat containing-1 (CTHRC1) is a 30 kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by limiting collagen matrix deposition and promoting cell migration. CTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, in the hypothalamus, pituitary gland and remodeling tissues. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with cancer invasion and metastasis. With adiponectin and other members of the C1q/TNF-related protein (CTRP) family, CTHRC1 shares the presence of a short N-terminal collagen domain but it lacks the characteristic C1q domain that defines the CTRP family of proteins. A recent study identifies CTHRC1 as a novel circulating hormone with metabolic effects.
- Molecular Weight
- ~Two bands of 25-30 kDa (SDS-PAGE)
- UniProt
- Q9D1D6
- Pathways
- Tube Formation
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