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CTHRC1 Protein (His tag)

CTHRC1 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318344
  • Target See all CTHRC1 Proteins
    CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))
    Protein Type
    Recombinant
    Origin
    • 8
    • 2
    • 2
    Human
    Source
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This CTHRC1 protein is labelled with His tag.
    Purpose
    Recombinant Human CTHRC1 Protein (His Tag)
    Sequence
    Ser31-Lys243
    Characteristics
    Recombinant Human Collagen triple helix repeat-containing protein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Lys243 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTHRC1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CTHRC1 (Collagen Triple Helix Repeat Containing 1 (CTHRC1))
    Alternative Name
    CTHRC1 (CTHRC1 Products)
    Synonyms
    CTHRC1 Protein, cthrc1 Protein, zgc:101075 Protein, 1110014B07Rik Protein, collagen triple helix repeat containing 1 Protein, collagen triple helix repeat containing 1a Protein, CTHRC1 Protein, cthrc1 Protein, cthrc1a Protein, Cthrc1 Protein
    Background

    Background: Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.

    Synonym: Collagen triple helix repeat-containing protein 1,Protein NMTC1,CTHRC1

    Molecular Weight
    24.1 kDa
    UniProt
    Q96CG8
    Pathways
    Tube Formation
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