Transferrin Receptor 2 Protein (TFR2) (partial) (Fc Tag)

Catalog No. ABIN5608299

Product Details

Target: Transferrin Receptor 2 (TFR2)

Protein Type: Recombinant

Protein Characteristics: partial

Origin: Mouse

Source: HEK-293 Cells

Purification tag / Conjugate: This Transferrin Receptor 2 protein is labelled with Fc Tag.

Application: Western Blotting (WB)

Sequence: Arg 103 - Phe 798

Purity: >95 % as determined by SDS-PAGE.

Endotoxin Level: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Application Details

Application Notes: This recombinant protein can be used for WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Target Details

Target: Transferrin Receptor 2 (TFR2)

Alternative Name: Transferrin R2 (TFR2 Products)

Synonyms: TFR2 Protein, Trfr2 Protein, HFE3 Protein, TFRC2 Protein, zgc:123043 Protein, transferrin receptor 2 Protein, TFR2 Protein, Tfr2 Protein, tfr2 Protein

Background: Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.

Molecular Weight: 103.2 kDa

Gene ID: 50765

UniProt: Q9JKX3

Pathways: Transition Metal Ion Homeostasis