Bcl-2 Protein (AA 5-205, partial) (His tag)
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- Target See all Bcl-2 (BCL2) Proteins
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 5-205, partial
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Bcl-2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GRTGYDNREI VMKYIHYKLS QRGYEWDAGD ADAAPLGAAP TPGIFSFQPE SNPMPAVHRD MAARTSPLRP LVATAGPALS PVPPVVHLTL RRAGDDFSRR YRRDFAEMSS QLHLTPFTAR GRFATVVEEL FRDGVNWGRI VAFFEFGGVM CVESVNREMS PLVDNIALWM TEYLNRHLHT WIQDNGGWDA FVELYGPSMR P
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product BCL2 Protein
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B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (GST tag)
BCL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 2 (BCL2) (AA 5-205) protein (His tag)BCL2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-211) protein (His-IF2DI Tag)BCL2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 140-239) protein (GST tag)BCL2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Alternative Name
- BCL2 (BCL2 Products)
- Synonyms
- Bcl-2 Protein, PPP1R50 Protein, bcl-2 Protein, AW986256 Protein, C430015F12Rik Protein, D630044D05Rik Protein, D830018M01Rik Protein, BCL-2 Protein, Bcl2 Protein, BCL2, apoptosis regulator Protein, B cell leukemia/lymphoma 2 Protein, B-cell CLL/lymphoma 2a Protein, B-cell CLL/lymphoma 2 protein Protein, BCL2 Protein, Bcl2 Protein, bcl2a Protein, BCL-2 Protein
- Background
- Suppresses apoptosis in a variety of cell systs including factor-dependent lymphohatopoietic and neural cells. Regulates cell death by controlling the mitochondrial mbrane permeability. Appears to function in a feedback loop syst with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
- Molecular Weight
- 26.8 kDa
- UniProt
- P10417
- Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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