IL1A Protein (AA 113-271) (His-SUMO Tag)

Catalog No. ABIN5709737

Product Details

Target: IL1A (Interleukin 1 alpha (IL1A))

Protein Type: Recombinant

Protein Characteristics: AA 113-271

Origin: Rhesus Monkey

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This IL1A protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: SAPFSFLSNM TYHFIRIIKH EFILNDTLNQ TIIRANDQHL TAAAIHNLDE AVKFDMGAYT SSKDDTKVPV ILRISKTQLY VSAQDEDQPV LLKEMPEINK TITGSETNFL FFWETHGTKN YFISVAHPNL FIATKHDNWV CLAKGLPSIT DFQILENQA

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL1A (IL1A Products)

Synonyms: IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein

Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Molecular Weight: 34.12 kDa

UniProt: P48089

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints