tau Protein (AA 2-459) (His-SUMO Tag)
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- Target See all tau Proteins
- tau (tau Protein)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-459
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Origin
- Rhesus Monkey
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This tau protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- AEPRQEFDVM EDHAGTYGLG DRKDQEGYTM LQDQEGDTDA GLKESPLQTP AEDGSEELGS ETSDAKSTPT AEDVTAPLVD ERAPGEQAAA QPHMEIPEGT TAEEAGIGDT PSLEDEAAGH VTQARMVSKS KDGTGSDDKK AKGADGKTKI ATPRGAAPPG QKGQANATRI PAKTPPAPKT PPSSATKQVQ RKPPPAEPTS ERGEPPKSGD RSGYSSPGSP GTPGSRSRTP SLPTPPAREP KKVAVVRTPP KSPSSAKSRL QTAPVPMPDL KNVKSKIGST ENLKHQPGGG KVQIINKKLD LSNVQSKCGS KDNIKHVPGG GSVQIVYKPV DLSKVTSKCG SLGNIHHKPG GGQVEVKSEK LDFKDRVQSK IGSLDNITHV PGGGNKKIET HKLTFRENAK AKTDHGAEIV YKSPVVSGDT SPRHLSNVSS TGSIDMVDSP QLATLADEVS ASLAKQGL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product tau Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- tau (tau Protein)
- Alternative Name
- tau (tau Products)
- Synonyms
- DDPAC Protein, FTDP-17 Protein, MAPTL Protein, MSTD Protein, MTBT1 Protein, MTBT2 Protein, PPND Protein, TAU Protein, tau Protein, PHF-tau Protein, microtubule associated protein tau Protein, MAPT Protein
- Background
- Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
- Molecular Weight
- 63.8 kDa
- UniProt
- P57786
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