PZP Protein (AA 472-821) (His tag)
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- Target See all PZP Proteins
- PZP (Pregnancy Zone Protein (PZP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 472-821
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PZP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MKPEAELSVS SVYNLLTVKD LTNFPDNVDQ QEEEQGHCPR PFFIHNGAIY VPLSSNEADI YSFLKGMGLK VFTNSKIRKP KSCSVIPSVS AGAVGQGYYG AGLGVVERPY VPQLGTYNVI PLNNEQSSGP VPETVRSYFP ETWIWELVAV NSSGVAEVGV TVPDTITEWK AGAFCLSEDA GLGISSTASL RAFQPFFVEL TMPYSVIRGE VFTLKATVLN YLPKCIRAEG IEQEKTFSSM TCASGANVSE QLSLKLPSNV VKESARASFS VLGDILGSAM QNIQNLLQMP YGCGEQNMVL FAPNIYVLNY LNETQQLTQE IKAKAVGYLI TGYQRQLNYK HQDGSYSTFG
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PZP Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PZP (Pregnancy Zone Protein (PZP))
- Alternative Name
- PZP (PZP Products)
- Synonyms
- A1m Protein, pregnancy zone protein Protein, pregnancy-zone protein Protein, CpipJ_CPIJ000348 Protein, Pzp Protein, PZP Protein
- Background
- Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme rains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
- Molecular Weight
- 42.3 kDa
- UniProt
- P20742
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